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Life Sciences · Pharmacology, Toxicology and Pharmaceutics

Pharmacy and Medical Practices
Research Guide

What is Pharmacy and Medical Practices?

Pharmacy and Medical Practices is the field encompassing pharmaceutical care and clinical pharmacy practice, including medication management, patient education, drug information, adverse drug reactions, community pharmacy services, pharmacist roles, healthcare communication, and pharmacy training.

This field covers pharmaceutical interventions, evaluation of training programs, patient satisfaction, and pharmacists' roles in optimizing medication therapy and ensuring patient safety. The cluster includes 57,942 works. Papers address potentially inappropriate medications in older adults and quality enhancement in healthcare delivery.

Topic Hierarchy

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graph TD D["Life Sciences"] F["Pharmacology, Toxicology and Pharmaceutics"] S["Pharmacology"] T["Pharmacy and Medical Practices"] D --> F F --> S S --> T style T fill:#DC5238,stroke:#c4452e,stroke-width:2px
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57.9K
Papers
N/A
5yr Growth
71.5K
Total Citations

Research Sub-Topics

Why It Matters

Pharmacy and Medical Practices guides medication safety in vulnerable populations, such as older adults, where potentially inappropriate medications lead to poor outcomes. The American Geriatrics Society Beers Criteria identify specific drugs to avoid, influencing clinical guidelines and policy. For example, misoprostol reduced serious NSAID-induced upper gastrointestinal complications by 40% in older patients with rheumatoid arthritis receiving nonsteroidal anti-inflammatory drugs (Silverstein et al., 1995). These criteria support clinicians, educators, researchers, and regulators in reducing adverse events and improving patient safety.

Reading Guide

Where to Start

"<scp>A</scp> merican <scp>G</scp> eriatrics <scp>S</scp> ociety Updated <scp>B</scp> eers <scp>C</scp> riteria for Potentially Inappropriate Medication Use in Older Adults" by The American Geriatrics Society 2012 Beers Criteria Update Expert Panel (2012) provides foundational explicit criteria on medication safety in older adults, serving as an accessible entry point with 2557 citations.

Key Papers Explained

The 2012 Beers Criteria paper by The American Geriatrics Society 2012 Beers Criteria Update Expert Panel (2557 citations) establishes core lists of potentially inappropriate medications, which Mark H. Beers (1997) (1046 citations) developed earlier through explicit criteria updates. The 2023 update by By the 2023 American Geriatrics Society Beers Criteria Update Expert Panel (1073 citations) refines these for current use. Silverstein et al. (1995) (1060 citations) complements by showing misoprostol's 40% reduction in complications, linking criteria to interventions. Khare and Kanyal (2024) (959 citations) extends to quality enhancement practices.

Paper Timeline

100%
graph LR P0["The Equation of the Characterist...
1947 · 2.1K cites"] P1["A Multiple Comparison Procedure ...
1955 · 1.4K cites"] P2["The Theory and Practice of Indus...
1970 · 1.2K cites"] P3["Misoprostol Reduces Serious Gast...
1995 · 1.1K cites"] P4["Accreditation Council for Pharma...
2003 · 1.4K cites"] P5["A merican G2012 · 2.6K cites"] P6["American Geriatrics Society 2023...
2023 · 1.1K cites"] P0 --> P1 P1 --> P2 P2 --> P3 P3 --> P4 P4 --> P5 P5 --> P6 style P5 fill:#DC5238,stroke:#c4452e,stroke-width:2px
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Most-cited paper highlighted in red. Papers ordered chronologically.

Advanced Directions

Recent works emphasize updates to Beers Criteria, with the 2023 version addressing stewardship and integration into practice. No preprints or news from the last 6-12 months indicate focus remains on established criteria and quality improvement applications.

Papers at a Glance

# Paper Year Venue Citations Open Access
1 <scp>A</scp> merican <scp>G</scp> eriatrics <scp>S</scp> ociet... 2012 Journal of the America... 2.6K
2 The Equation of the Characteristic Curve of Activated Charcoal 1947 Proceedings of the USS... 2.1K
3 Accreditation Council for Pharmacy Education 2003 Annals of Pharmacotherapy 1.4K
4 A Multiple Comparison Procedure for Comparing Several Treatmen... 1955 Journal of the America... 1.4K
5 The Theory and Practice of Industrial Pharmacy 1970 Journal of Pharmaceuti... 1.2K
6 American Geriatrics Society 2023 updated AGS Beers Criteria® f... 2023 Journal of the America... 1.1K
7 Misoprostol Reduces Serious Gastrointestinal Complications in ... 1995 Annals of Internal Med... 1.1K
8 Explicit Criteria for Determining Potentially Inappropriate Me... 1997 Archives of Internal M... 1.0K
9 Fundamentals of Clinical Pharmacokinetics 1975 1.0K
10 The Overview on Effectiveness of Quality Enhancement for Enhan... 2024 International Journal ... 959

Frequently Asked Questions

What are the Beers Criteria?

The Beers Criteria are explicit lists identifying potentially inappropriate medications for older adults due to high risk of adverse outcomes. The American Geriatrics Society 2012 Beers Criteria Update Expert Panel developed updated versions incorporated into policy and practice (The American Geriatrics Society 2012 Beers Criteria Update Expert Panel, 2012). The 2023 update continues stewardship by the American Geriatrics Society Beers Criteria Update Expert Panel (By the 2023 American Geriatrics Society Beers Criteria Update Expert Panel, 2023).

How does misoprostol affect NSAID users with rheumatoid arthritis?

Misoprostol reduces serious gastrointestinal complications in patients with rheumatoid arthritis taking nonsteroidal anti-inflammatory drugs. In older patients, it lowered these complications by 40% compared to placebo (Silverstein et al., 1995). This demonstrates a targeted pharmaceutical intervention for gastrointestinal protection.

What defines potentially inappropriate medication use in the elderly?

Explicit criteria determine potentially inappropriate medication use by the elderly based on risks of clinically severe adverse outcomes. Mark H. Beers (1997) updated and expanded these criteria, incorporating clinical information on diagnoses where available. The criteria measure poor outcomes associated with certain drugs in older adults.

What is continuous quality improvement in pharmacy practice?

Continuous quality improvement applies manufacturing techniques to healthcare for better standards, safety, and effectiveness. Khare and Kanyal (2024) overview its use in reorganizing service structure and delivery. It enhances professional practice in pharmacy and medical settings.

What role do pharmacists play in medication management?

Pharmacists optimize medication therapy and ensure patient safety through pharmaceutical care and clinical practice. Papers cover medication management, adverse drug reactions, and community pharmacy services. Training programs evaluate patient education and healthcare communication.

Open Research Questions

  • ? How can Beers Criteria be further refined to incorporate emerging pharmacogenetic data for personalized avoidance of inappropriate medications in older adults?
  • ? What factors limit the adoption of continuous quality improvement techniques from industry into diverse pharmacy practice settings?
  • ? How do explicit criteria for inappropriate medications account for evolving comorbidities and polypharmacy in aging populations?
  • ? In what ways can pharmaceutical interventions like misoprostol be optimized for broader patient groups beyond rheumatoid arthritis?

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