PapersFlow Research Brief
Anorectal Disease Treatments and Outcomes
Research Guide
What is Anorectal Disease Treatments and Outcomes?
Anorectal disease treatments and outcomes refer to surgical procedures and their results for conditions such as hemorrhoids, anal fistulas, pilonidal sinus, and rectovaginal fistulas, including techniques like stapled hemorrhoidopexy, anal fistula plug, endorectal advancement flap, ligation of intersphincteric fistula tract, and transanal hemorrhoidal dearterialization.
This field encompasses 48,308 papers on advancements in anorectal surgical procedures. Key techniques address hemorrhoids, fistulas, pilonidal sinus, and rectovaginal fistulas. Growth rate over the past 5 years is not available.
Topic Hierarchy
Research Sub-Topics
Stapled Hemorrhoidopexy
This sub-topic covers surgical resection of prolapsed hemorrhoidal tissue using circular staplers, assessing long-term outcomes and complications. Researchers compare it to traditional hemorrhoidectomy via RCTs on recurrence and continence.
Anal Fistula Plugs
Studies evaluate bioprosthetic plugs for closing complex anal fistulas, focusing on success rates, MRI outcomes, and sphincter preservation. Researchers investigate plug migration, infection, and comparisons with seton placement.
Ligation of Intersphincteric Fistula Tract
This area examines LIFT procedure for transsphincteric fistulas, involving ligation of the intersphincteric tract. Research tracks healing rates, recurrence, and modifications like FiLaC integration.
Endorectal Advancement Flap
Research assesses mucosal advancement flaps for fistula repair, optimizing flap design, tissue healing, and adjuncts like fibrin glue. Studies report on failure modes and outcomes in rectovaginal fistulas.
Transanal Hemorrhoidal Dearterialization
This sub-topic investigates THD with mucopexy for hemorrhoids, using Doppler-guided ligation of feeding arteries. Researchers evaluate symptom relief, prolapse correction, and long-term durability.
Why It Matters
Treatments for anorectal diseases impact patient quality of life by addressing fecal incontinence and pelvic floor dysfunction, which affect a substantial proportion of women and increase with age, as shown in Nygaard (2008) reporting prevalence data in US women. Olsen et al. (1997) found an 11.1% lifetime risk of surgery for pelvic organ prolapse and urinary incontinence, with many reoperations, highlighting the need for effective procedures to reduce recurrence. Jorge and Wexner (1993) detailed management of fecal incontinence, involving mechanisms like altered rectal compliance and anorectal sensation, where surgical outcomes determine continence restoration in conditions linked to anorectal pathology.
Reading Guide
Where to Start
'Etiology and management of fecal incontinence' by Jorge and Wexner (1993), as it provides foundational understanding of incontinence mechanisms directly relevant to anorectal disease pathophysiology and treatment principles.
Key Papers Explained
Olsen et al. (1997) in 'Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence' establishes epidemiological risks like 11.1% lifetime surgery rates, which Haylen et al. (2009) in 'An international urogynecological association (IUGA)/international continence society (ICS) joint report on the terminology for female pelvic floor dysfunction' builds on with standardized terminology for dysfunction assessment. Jorge and Wexner (1993) in 'Etiology and management of fecal incontinence' connects etiology to management, complemented by Heald et al. (1982) in 'The mesorectum in rectal cancer surgery—the clue to pelvic recurrence?' for surgical precision in rectal outcomes. Avery et al. (2004) in 'ICIQ: A brief and robust measure for evaluating the symptoms and impact of urinary incontinence' adds outcome measurement tools linking back to these foundations.
Paper Timeline
Most-cited paper highlighted in red. Papers ordered chronologically.
Advanced Directions
Current frontiers focus on refining techniques like stapled hemorrhoidopexy and ligation of intersphincteric fistula tract, as described in the field overview, with integration of fecal incontinence management from Jorge and Wexner (1993) and pelvic floor terminology from Haylen et al. (2009). No recent preprints or news available.
Papers at a Glance
Frequently Asked Questions
What is the lifetime risk of surgery for pelvic organ prolapse and urinary incontinence?
Olsen et al. (1997) in 'Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence' reported an 11.1% lifetime risk of undergoing a single operation for these conditions. A large proportion of cases involve reoperations. These findings underscore pelvic floor dysfunction as a major health issue for older women.
What mechanisms contribute to fecal incontinence in anorectal diseases?
Jorge and Wexner (1993) in 'Etiology and management of fecal incontinence' identified multiple mechanisms including altered stool consistency, abnormal rectal capacity or compliance, and decreased anorectal sensation. These factors lead to diverse etiology with psychosocial impact. Management targets these pathophysiology components.
What terminology exists for female pelvic floor dysfunction related to anorectal conditions?
Haylen et al. (2009) in 'An international urogynecological association (IUGA)/international continence society (ICS) joint report on the terminology for female pelvic floor dysfunction' provided a clinically based consensus for updated terminology. It addresses increasing complexity in lower urinary tract and pelvic floor issues. The report combines expert input for female-specific approaches.
How is urinary incontinence impact measured in anorectal disease outcomes?
Avery et al. (2004) in 'ICIQ: A brief and robust measure for evaluating the symptoms and impact of urinary incontinence' developed the International Consultation on Incontinence Questionnaire (ICIQ). This tool assesses symptoms and quality of life impact robustly. It resulted from systematic literature review and testing.
What role does the mesorectum play in rectal cancer surgery outcomes?
Heald et al. (1982) in 'The mesorectum in rectal cancer surgery—the clue to pelvic recurrence?' demonstrated minute adenocarcinoma foci in the mesorectum distal to tumors. This finding explains pelvic recurrence risks in orthodox resections. Precise mesorectal excision reduces such spread.
What is the prevalence of symptomatic pelvic floor disorders?
Nygaard (2008) in 'Prevalence of Symptomatic Pelvic Floor Disorders in US Women' showed these disorders affect a substantial proportion of US women. Prevalence increases with age. The study provides key epidemiological data.
Open Research Questions
- ? How can reoperation rates for pelvic organ prolapse and urinary incontinence be reduced below current levels observed in 11.1% lifetime risk cohorts?
- ? What precise interventions improve anorectal sensation and rectal compliance in fecal incontinence patients with diverse etiologies?
- ? How does mesorectal excision technique variation affect distal tumor spread and pelvic recurrence in rectal cancer cases?
- ? Which standardized terminology updates best integrate with surgical outcome metrics for female pelvic floor dysfunction?
- ? What factors drive age-related increases in symptomatic pelvic floor disorder prevalence and their anorectal treatment implications?
Recent Trends
The field maintains 48,308 papers with no specified 5-year growth rate.
High-citation works like Olsen et al. with 3321 citations continue to anchor epidemiology, while Haylen et al. (2009) at 2969 citations standardize terminology.
1997No recent preprints or news coverage reported.
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